GUANOLOGY unveils the PreterNatural potency of the Guanabana…
Guanabana: Nature’s Bio-Intelligent Superfruit
At the heart of Guanology™ is a tropical powerhouse: guanabana (also known as soursop or Annona muricata). Revered in traditional wellness across Central and South America, Africa, and Southeast Asia, this fruit has long been used to support skin, body, and balance. But its real power lies in something modern skincare has yet to fully embrace: its rare, naturally bio-intelligent compounds called acetogenins. Rare compounds. Proven potential. Cellular-level skincare.
Acetogenins: The Compounds That Changed Everything
Guanabana contains the highest known potency and consistency of a compound family called acetogenins—extraordinary molecules found almost exclusively in the Annonaceae plant family. Unlike standard actives that sit on the surface, acetogenins:
- Support deep cellular balance
- Help calm visible inflammation
- Aid in preserving healthy skin cells
- Promote resilience from oxidative stress and environmental damage
Guanologist™, Cheryl Boyle and chemist Peter Bohm: Guanology Research and Development.
Science-Backed Bioactivity
—Recent preclinical studies highlight acetogenins’ unique effects on the skin:
Mitochondrial Modulation
Acetogenins help rebalance energy production inside skin cells—supporting a calm, resilient complexion. Durán et al., 2021 – Molecules (MDPI)
https://www.mdpi.com/1420-3049/26/10/2926
Antioxidant Boost
Guanabana extracts increase antioxidant enzymes like SOD and catalase—fighting oxidative stress and supporting recovery. Moghadamtousi et al., 2015 – International Journal of Molecular Sciences. https://www.mdpi.com/1422-0067/16/7/15625
Cellular Selectivity
These compounds appear to preserve healthy cells while neutralizing stressed ones—working where your skin needs it most. Chen et al., 1998 – Phytochemistry (ScienceDirect) https://www.sciencedirect.com/science/article/abs/pii/S0031942297005975
A Skin-Nourishing Nutrient Profile
Guanabana is more than acetogenins—it’s a nutrient-dense fruit packed with skin-supportive actives:
Alkaloids – Soothe irritation and support a smooth, even look.
Flavonoids – Neutralize free radicals and help reduce visible redness.
Vitamins (C, B1, B2, B3, B5, B6, B9) – Brighten tone, support collagen, and improve resilience.
Vitamin E (tocopherols) – Antioxidant defense; helps strengthen the skin barrier and retain moisture.
Carotenoids (incl. β-carotene/Vitamin A) – Support elasticity, regeneration, and a healthy glow.
Cyclopeptides – Encourage recovery, smoothness, and refined texture.
Essential Fatty Acids (Omega 3, Omega 6, Omega 9) – Deeply nourish, reinforce the moisture barrier, and help calm visible irritation.
Essential Minerals (K, Mg, Fe, Cu, Ca) – Help balance hydration, aid repair, and protect overall skin function.
Rooted in Tradition, Refined by Science
For centuries, guanabana has been valued across cultures for its soothing, restorative properties—from postpartum recovery in South America to skin-calming rituals in tropical Africa. Today, modern research is just beginning to validate what traditional wisdom always knew: this fruit was ahead of its time.
Cleanly Extracted. Cold Processed. Clinically Minded.
At Guanology™, we protect the natural potency of guanabana using cold-process methods and formula integrity—preserving what nature made powerful. Our mission? Delivering skincare that works with your skin’s own intelligence to restore, rebalance, and radiate.